CJC-1295 with DAC 2mg

CJC-1295 with DAC – 2 mg

CJC-1295 with DAC (Drug Affinity Complex) is a synthetic analog of growth hormone-releasing hormone (GHRH), engineered for extended half-life through albumin binding. It’s designed to stimulate prolonged release of endogenous growth hormone (GH) and insulin-like growth factor 1 (IGF-1), while minimizing pulsatile dosing. Supplied as a lyophilised powder for research use only, it serves as a powerful tool in studies of hormone axis regulation, tissue metabolism, and recovery pathways.

Research Focus and Areas of Interest

1. Prolonged GH-IGF-1 Release

CJC-1295 with DAC maintains elevated GH and IGF-1 levels for multiple days post-administration, supporting investigations into sustained anabolic signaling and endocrine feedback regulation.

2. GHRH Receptor Activation

As a modified GHRH analog, it binds the GHRH receptor in the anterior pituitary to drive GH secretion in a controlled, sustained manner—ideal for research into hormonal cascade dynamics.

3. Metabolic and Tissue Applications

Researchers explore its utility in examining changes in lean mass, fat metabolism, and tissue remodeling through GH/IGF-1 mediated pathways.

4. Comparative Pharmacokinetics

CJC-1295 with DAC contrasts sharply with the non-DAC form in half-life and dosing frequency—an important variable in experimental design considering temporal hormone dynamics and receptor feedback.

Conclusion

CJC-1295 with DAC is a robust research peptide for modeling prolonged endogenous GH/IGF-1 axis activation. It offers a controlled system for studying anabolic pathways, endocrine signaling, and metabolic regulation. Supplied strictly for research use only, it is not intended for human or veterinary application.

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Technical Information:

• Synonyms: CJC-1295 DAC; DAC:GRF (Drug Affinity Complex–GHRH analog)

• Modified Single-Letter Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC

• IUPAC Condensed Amino Acid Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC

• Molecular Weight: ~3648 g/mol

• CAS Number: 446262-90-4

• PubChem CID: 56841945

• Further Reference: PubChem Link

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Stability, Source, and Handling

• Stability: Stable up to 36 months when stored at –20 °C or colder, protected from light and moisture.

• Source: Synthesized using solid-phase peptide methods and supplied with Certificate of Analysis (COA) confirming purity and identity.

• Reconstitution: Dissolve in sterile water or PBS under aseptic conditions; aliquot and store at –80 °C following reconstitution to minimize degradation.

• Usage: Product is prepared for LABORATORY RESEARCH ONLY. Intended for controlled in-vitro and in-vivo laboratory protocols.

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